Control of Axonal Growth and Regeneration of Sensory Neurons by the p110δ PI 3-Kinase
Britta J. Eickholt, Aminul I. Ahmed, Meirion Davies et al. · 2007
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Description
Britta Eickholt, Aminul Ahmed, Meirion Davies and co-authors studied a single enzyme form called p110 delta in nerve growth, for PLOS ONE in 2007. The enzyme belongs to the PI 3-kinase family, which has eight forms whose roles in the nervous system were unclear. The p110 delta form was mostly known from white blood cells.
The team asked what this form does in sensory neurons, the cells that carry signals from skin and muscle. They focused on how axons, the long fibers of nerve cells, grow and regrow after damage. Knowing which enzyme form drives regrowth could guide later work on nerve repair.
Catalog record
| CREATOR | Britta J. Eickholt, Aminul I. Ahmed, Meirion Davies et al. |
|---|---|
| YEAR | 2007 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| LICENSE | Creative Commons Attribution License |
| RIGHTS | CC BY |
| SOURCE | PLOS ONE |
Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000869