Brain Expressed microRNAs Implicated in Schizophrenia Etiology

Thomas Hansen, Line Olsen, Morten Lindow et al. · 2007

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Description

Thomas Hansen, Line Olsen, Morten Lindow and colleagues searched for brain microRNAs tied to schizophrenia, in PLOS ONE in 2007. Genes that code for proteins have long been the main target in schizophrenia genetics. MicroRNAs are short pieces of RNA that tune how genes are used, and they play a real part in brain growth and function.

That made microRNA genes fresh candidates for the search. The team focused on ones active in the brain and checked them for links to the illness. Work like this widens the hunt beyond protein genes alone. It also fits a view of schizophrenia as a disorder of how brain circuits are built and tuned.

Catalog record

CREATORThomas Hansen, Line Olsen, Morten Lindow et al.
YEAR2007
COLLECTIONPAPERS
FORMATTXT
FILE SIZE35 KB
LICENSECreative Commons Attribution License
RIGHTSCC BY
SOURCEPLOS ONE

Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000873

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