Potential Impact of Antiretroviral Chemoprophylaxis on HIV-1 Transmission in Resource-Limited Settings
Ume L. Abbas, Roy M. Anderson, John W. Mellors · 2007
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Description
Ume Abbas, Roy Anderson and John Mellors modeled whether preventive HIV drugs could slow spread in poorer settings, in PLOS ONE in 2007. The idea, called pre-exposure prophylaxis, is to give antiretroviral drugs to people before exposure. Whether it would help across a whole epidemic in sub-Saharan Africa was unclear.
The authors used a math model of heterosexual HIV spread to test the approach. Models like this let planners weigh benefit, cost and risk before a policy is tried at scale. Their work speaks to a hard choice: a tool that protects one person must also help, or at least not harm, the wider fight against the virus.
Catalog record
| CREATOR | Ume L. Abbas, Roy M. Anderson, John W. Mellors |
|---|---|
| YEAR | 2007 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55 KB |
| LICENSE | Creative Commons Attribution License |
| RIGHTS | CC BY |
| SOURCE | PLOS ONE |
Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000875