Metabolome Based Reaction Graphs of M. tuberculosis and M. leprae : A Comparative Network Analysis

Ketki D. Verkhedkar, Karthik Raman, Nagasuma R. Chandra et al. · 2007

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Description

Ketki Verkhedkar, Karthik Raman, Nagasuma Chandra and co-authors compared reaction networks in the germs behind tuberculosis and leprosy, for PLOS ONE in 2007. Scientists build many kinds of maps for living systems, from gene control maps to maps of chemical reactions. Each map gives a different view of how a cell runs.

Here the team built graphs from the metabolome, the full set of small chemicals in the cell, for Mycobacterium tuberculosis and Mycobacterium leprae. Comparing the two may show where their chemistry is shared and where it parts. Those differences matter, since one germ causes TB and the other leprosy, two very different diseases.

Catalog record

CREATORKetki D. Verkhedkar, Karthik Raman, Nagasuma R. Chandra et al.
YEAR2007
COLLECTIONPAPERS
FORMATTXT
FILE SIZE61 KB
LICENSECreative Commons Attribution License
RIGHTSCC BY
SOURCEPLOS ONE

Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000881

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