Prediction of RNA Pseudoknots Using Heuristic Modeling with Mapping and Sequential Folding
Wayne K. Dawson, Kazuya Fujiwara, Gota Kawai · 2007
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Description
Wayne Dawson, Kazuya Fujiwara and Gota Kawai offered a practical way to predict knots in RNA folding, in PLOS ONE in 2007. Predicting how an RNA strand folds is often the first step toward knowing its structure. Most tools skip pseudoknots, folded loops that cross each other, because searching for them is slow and complex.
Skipping them, though, leaves real structures out of reach. The authors use heuristic modeling, guided shortcuts, with mapping and step by step folding to make the search workable. Better folding guesses help everyone who studies RNA viruses, gene control and RNA based drugs. The paper is aimed at users who need answers in real time.
Catalog record
| CREATOR | Wayne K. Dawson, Kazuya Fujiwara, Gota Kawai |
|---|---|
| YEAR | 2007 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| LICENSE | Creative Commons Attribution License |
| RIGHTS | CC BY |
| SOURCE | PLOS ONE |
Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000905