ADAM33 , a New Candidate for Psoriasis Susceptibility

Fabienne Lesueur, Tiphaine Oudot, Simon Heath et al. · 2007

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Description

Fabienne Lesueur, Tiphaine Oudot, Simon Heath and colleagues named ADAM33 as a fresh candidate gene for psoriasis, in PLOS ONE in 2007. Psoriasis is a long lasting skin disorder with many causes, genes among them. An earlier genome scan in forty-six French families with plaque psoriasis had already pinned down one major risk region.

Building on that scan, the team point to ADAM33 as another possible contributor. A candidate is not proof, and the authors present it as a lead to test. Each solid lead matters because psoriasis treatment still relies heavily on broad immune calming. A gene based lead could one day point to a narrower target.

Catalog record

CREATORFabienne Lesueur, Tiphaine Oudot, Simon Heath et al.
YEAR2007
COLLECTIONPAPERS
FORMATTXT
FILE SIZE46 KB
LICENSECreative Commons Attribution License
RIGHTSCC BY
SOURCEPLOS ONE

Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000906

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