Direct Selection on Genetic Robustness Revealed in the Yeast Transcriptome
Stephen R. Proulx, Sergey Nuzhdin, Daniel E. L. Promislow · 2007
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Description
Stephen Proulx, Sergey Nuzhdin and Daniel Promislow looked for direct selection on genetic robustness in yeast, in PLOS ONE in 2007. Theory says living things should evolve ways to keep a healthy form despite shocks from outside or from their own mutations. Several routes to that steadiness were already known.
What was missing was proof that selection acts on robustness itself, not just on traits it protects. Reading the yeast transcriptome, the full set of active genes, the authors argue the signature is there. The claim matters for how we think traits stay stable over generations. It also bears on why some mutations stay hidden until stress reveals them.
Catalog record
| CREATOR | Stephen R. Proulx, Sergey Nuzhdin, Daniel E. L. Promislow |
|---|---|
| YEAR | 2007 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| LICENSE | Creative Commons Attribution License |
| RIGHTS | CC BY |
| SOURCE | PLOS ONE |
Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000911