Comparative Analysis of E2F Family Member Oncogenic Activity

Chunxia Chen, Andrew D. Wells · 2007

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Description

Chunxia Chen and Andrew Wells compared the cancer linked power of the E2F factor family, in a 2007 PLOS ONE study. The E2F family has nine members with jobs that are partly distinct and partly shared. These factors sit below growth signals and help decide whether a cell grows and divides.

Because they control genes tied to cell growth, some members may push cancer more than others. Chen and Wells set the members side by side to compare their oncogenic activity, their ability to drive tumor like growth. A clear ranking helps cancer research focus on the members that matter most, instead of treating the family as one block.

Catalog record

CREATORChunxia Chen, Andrew D. Wells
YEAR2007
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32 KB
LICENSECreative Commons Attribution License
RIGHTSCC BY
SOURCEPLOS ONE

Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000912

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